Enzyme-directed Evolution Services

丨 Introduction

At Molefuture, we provide comprehensive solutions for innovative enzyme applications across various industries, including enzyme-directed evolution, novel enzyme discovery and development, enzyme production process development, and commercial scaling up of enzyme production. By integrating directed evolution with rational design, and employing interactive screening processes, we have established a robust technical foundation for the creation of high-performance enzymes. Our experts custom-tailors enzyme designs and optimizations to meet the precise needs of your project, ensuring biocatalyst efficiency at every stage.

进化流程图.jpg

Workflow of ZymeEditor platform

丨 Technology platform

Molefuture has developed the ZymeEditor platform, which incorporates cutting-edge enzyme evolution technologies, including Fluorescence-Activated Droplet Sorting (FADS), alongside traditional methods like Microtiter Plate Screening (MTPS) and Computer-Aided Rational Design (CARD). The high throughput FADS, with its capability to screen up to 10^6 variants per day, alongside traditional methods for advanced and efficient enzyme optimization. Through cross-screening utilizing these technologies, our platform significantly enhances the efficacy of enzyme evolution, ensuring a high success rate in refining enzyme characteristics(activity, stability, selectivity, etc).

FADS图片.png

FADS platform

丨 Edge in Customized Enzyme Evolution Service

Technical Strength

With the expertise of directed evolution technology, inspired by the Nobel laureate Professor Frances H. Arnold, Molefuture has developed the ZymeEditor platform, integrating five core enzyme evolution technologies to establish a robust technical foundation for creating high-performance enzymes.

Short Cycle, Quick Results

Harness the power of high-throughput FADS for enzyme optimization needs, boasting the remarkable capability to screen up to 10^6 variants daily. This high-throughput system complements traditional methods, ensuring a reliable and rapid process.

Expertise Through Experience

We have successfully engineered a diverse range enzymes, encompassing monooxygenases, esterases, ligases, T7 RNA polymerase, Bst DNA polymerase, and Taq DNA polymerase. With more than 30 proprietary intellectual property rights, we showcase our robust capabilities in enzyme engineering.

丨 Case Studies